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  • buy cheap productsMastering Modafinil: A Comprehensive Guide to Its Benefits and Health Risks

Mastering Modafinil: A Comprehensive Guide to Its Benefits and Health Risks

Mastering Modafinil: A Comprehensive Guide to Its Benefits and Health Risks

Last updated on 30 Nov, 2023

Modafinil is a non-amphetamine CNS stimulant that is approved for Excessive Daytime Sleepiness. It is marketed online as a 'smart drug' and keeps you alert and focused for long periods of time with minimal side effects and abuse potential.

Are you wondering what is Modafinil? If yes, then you are just in the right place.

This comprehensive guide explains everything that one must know about this Nootropic. Right from its uses and benefits to its warnings, adverse effects, and affordability, we have everything in one place just for you.

So, let us see what Modafinil is and if it is safe to follow the crowd and get Modafinil online.

What Is Modafinil?

Modafinil is used as a wake-promoting Central Nervous System stimulant that works within 30 minutes of intake. Modafinil can treat excessive daytime sleepiness due to Narcolepsy, Obstructive Sleep Apnea, and Shift work sleep disorders.

Modafinil is also known for its off-label benefits, including depression, ADHD, fatigue, and better cognitive functioning.

How Was Modafinil Discovered?

In 1974, two French scientists working for the pharmaceutical company Lafon Ltd. discovered a compound. Later, this compound was named Adrafinil. Many tests were made, which proved Adrafinil to be a strong wakefulness-promoting agent.

Adrafinil was trialed several times for the treatment of Narcolepsy, but it made people feel drowsy. The attempts failed. Finally, in 1976, an active metabolite of Adranil was born, which led to the formation of Modafinil [1].

Modafinil Mechanism Of Action

The Modafinil drug is readily absorbed by the body and has a dose-dependent pharmacokinetic range of 200 to 600 mg. It reaches a peak plasma concentration between 2 and 4 hours after dosing.

The metabolism of Modafinil takes place in the liver and is further eliminated through the kidney.

Modafinil is a weak dopamine reuptake inhibitor that binds to the dopamine transporter (DAT). This interaction can increase the level of dopamine in the body, causing a wake-promoting effect.

Modafinil also promotes the secretion of norepinephrine, Histamine, and serotonin, which is known to cause arousal in the user.

What Is Modafinil 200 Mg Used For?

Modafinil, as a stimulant, is used for treating sleep disorders. It is effective for the treatment of Narcolepsy, Obstructive Sleep Apnea, and Shift work disorders.

The off-label benefit of Modafinil has numerous benefits, such as-

  • Improvement of memory

  • Greater concentration and focus.

  • Enhancement of executive functioning.

  • Boosting energy, thus managing chronic fatigue.

Studies also suggest that the use of Modafinil for ADHD (Attention-deficit/hyperactivity disorder) and cocaine addiction is an effective treatment option with lower health risks [2,3].

What Are The Different Brand Names For Modafinil?

Modafinil is available in numerous brand drugs, which are formulated with the same active compound and show similar potency and benefits. Some of the popular Modafinil brand drugs are listed below with their manufacturing pharmaceutical companies.

  • Modalert - Manufactured by Sun Pharmaceuticals. It is the premier generic form of Modafinil. This claims to boost your power of cognition for 10-12 hours.

  • Modvigil- It is manufactured by HAB Pharmaceuticals. It is considered the second most generic form of Modafinil. The half-life is considered to be 10-13 hours in comparison to Modalert, which is 12-14 hours.

  • Modafinil MD- These are some of the unique brands that are sent from India. It is manufactured under the name biopharmaceuticals. This tablet generally works faster because you need to hold it under your tongue for 10-15 minutes. The tablet completely dissolves and starts working in under 15 minutes.

  • Vilafinil- This generic form also comes from an Indian Company named Centurion Laboratories. The strength is almost similar but a bit more expensive.

  • Modafresh- It is manufactured by Sunrise Pharmaceuticals. Although this is a newer variant, it has quite a few similarities with Modvigil in terms of potency.

  • Modawake- It is manufactured by HAB Pharmaceuticals. It was stated by the Smart Drug Community that it is the Inferior version of Modvigil (4).

Modafinil Dosing Guidelines

The goal of people who buy Modafinil without a prescription for its off-label benefits is to maximize its cognitive-enhancing properties while minimizing its potential health risks. So, how do you do that? The secret is to take the right dosage.

Modafinil Dosage For Obstructive Sleep Apnea And Narcolepsy

Generally, the recommended dose of Modafinil for Narcolepsy and Obstructive sleep apnea is 200 mg/day. It is best to take the dose in the morning to avoid insomnia.

Modafinil For Shift Work Disorder

Modafinil 200 mg must be taken about 30 minutes to 1 hour prior to work.

Administration- How To Take Modafinil?

  • The Modafinil oral tablets should be taken once daily, preferably in the morning.

  • The Modafinil dose should not be broken or crushed before administration.

  • It can be taken before or after a meal.

  • Consumption of alcohol is not recommended with Modafinil as it may result in dizziness and drowsiness.

  • Avoid the intake of grapefruit with Modafinil.

What Should I Keep In Mind While Taking Modafinil 200mg?

There are certain precautionary measures that need to be kept in mind while consuming Modafinil 200mg.

1. Less caffeine intake while consuming Modafinil.

2. Consultation from your medical experts.

3. Frequent blood pressure.

4. Buy Modafinil during pregnancy only after consulting with health experts.

5. Consult a doctor to find alternative birth control, as Modafinil can make most contraceptives ineffective.

Modafinil Side-effects


Headache, dizziness, and drowsiness are some of the common side effects of Modafinil. These are mild conditions and do not require immediate medical help.

In comparison, some of the other severe side effects include depression, changes in mood, and difficulty breathing. Changes in heart rate by Modafinil are also commonly reported. If you come across any of these side effects, it is best to discontinue the treatment and consult a doctor immediately.

Allergic reactions to Modafinil are rare; however, symptoms like swollen lymph nodes, rashes on your skin, and swelling of your face and tongue have been reported in a few cases.

Modafinil Interaction With Other Drugs

Modafinil can interact with 458 medications, which may affect its potency or increase the number of serious adverse effects.

Some of the medications that should not be taken with Modafinil are listed below; however, this is not a complete list of all the possible Modafinil interactions. Consult a doctor before taking any other medication or supplement with Modafinil 200 mg.

  1. Axitinib

  2. Bosutinib

  3. Daridorexant

  4. Elacestrant

  5. Coffee- A high amount of caffeine can speed up the occurrence of side effects.

  6. Other Nootropics- Modafinil and Armodafinil, are similar in nature and thus should not be used simultaneously.

Modafinil Cost And Vendors In the USA

Modafinil is a Schedule IV controlled substance whose purchase, refill, and distribution are regulated by the Drug Enforcement Administration (DEA). Thus, Modafinil 200 tablets are not available over the counter without a prescription.

Online Modafinil vendors may be a great option to buy the medication without consulting a doctor. However, it is essential to be careful and alert while choosing them.

Healthmatter is an online pharmacy dedicated to making healthcare services in the USA affordable, reliable, and accessible to all. We relentlessly try to offer pocket-friendly Modafinil 200 mg tablets online to our customers by directly getting the medications from the manufacturer. It also helps us maintain the highest standards and quality of all our products. The cost of Modafinil at Healthmatter is $1.01 per pill. This cost may, however, differ depending on the country, pharmacy, and pill package.

Every purchase of Modafinil from Healthmatter guarantees-

  • Free shipping

  • A tracking number against the product shipment.

  • Hassle-free return and refund

  • Safe Payment gateways

  • 24X7 customer support

Modafinil Pills: The Key Takeaway

Modafinil generally comes in 100 to 200 mg oral dosages. Modafinil is an active, stimulating agent that helps in the treatment of excessive sleepiness. Its effect on the brain helps to induce better cognitive enhancement, including better memory, creativity, concentration, and attention span.

People often take Modafinil for exercise as it helps in improving endurance and lower fatigue, which helps them work out for a longer period. It also helps such people stay focused and avoid any distractions, which is a common reason to avoid the gym.

Modafinil is a well-tolerated, safe medication with a low risk of side effects. It takes 30 minutes to work, and its action lasts for about 12 hours.

The use of Modafinil is not safe under the following health conditions.

  • If you suffer from anxiety, depression, or any other mental disorder.

  • If you are taking prescription drugs that can interact with Modafinil.

  • Taking contraceptive pills.

  • If you are pregnant or breastfeeding.


Modafinil is used to treat excessive sleepiness. Conditions like Narcolepsy, Shiftwork disorder, and Obstructive sleep apnea are some of the diseases treated by Modafinil.

Modafinil, as a stimulant, affects the mind and causes feelings of alertness. However, the consumption of Modafinil in large amounts can lead to habit formation, which can lead to addiction.

Modafinil, under the brand name Provigil, acts as a Central Nervous System stimulant drug. It is often referred to as an Eurogenic medication.

The recommended dose for Modafinil is 200 mg/day. It is found to have low adverse effects and to be well tolerated.

It is found to be 12-15 hours in humans. It was commercialized in the year 2003.


  1. History Of Modafinil, Modafinil
  2. A double-blind, placebo-controlled trial of modafinil for cocaine dependence, PubMed. 
  3. A comparison of once-daily and divided doses of modafinil in children with attention-deficit/hyperactivity disorder: a randomized, double-blind, and placebo controlled study, PubMed.  
  4. Generic Modafinil brands, modafinil.


Disclaimer: We do not provide any medical advice.

The contents of HealthMatter are for informational purpose only and is taken by a thorough evaluation of research papers and Journals. We do not provide professional medical advice, treatment, or diagnosis. We advise all readers to consult a physician before consuming any medication mentioned on the website.