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Nootropics Armodafinil vs Modafinil | Modafinil vs Armodafinil

Nootropics Armodafinil vs Modafinil | Modafinil vs Armodafinil

Last updated on 14 Oct, 2022

Armodafinil vs. Modafinil- If you are struggling in choosing between the two most effective Nootropics, we have you covered.

Both Armodafinil and Modafinil are prescription medicines and are approved by the FDA for treating excessive daytime sleepiness. They are also well-known for their numerous off-label benefits. 

Choosing between their therapeutic benefits and establishing which is better can be very tedious, so let us have a better insight on Armodafinil and Modafinil and establish the right one for you. 

Armodafinil vs Modafinil- An overview of the Nootropics 

Modafinil 200mg:

Modafinil is available under the brand name Provigil, Modvigil, and Modalert. The high efficacy of the Modafinil brand makes the comparison between Modalert vs Modvigil common. In addition, it is very effective in reducing the sign of excessive daytime sleepiness arising from sleep disorders such as shift work sleep disorder, narcolepsy, and obstructive sleep apnea. The off-label uses of Modafinil include enhancing cognition in people. Modafinil 200 mg is approximately $1 per pill, making it affordable. 

Armodafinil 150mg:

Armodafinil is an enantiopure compound of Modafinil. Moreover, this Nootropic contains Modafinil's (R)-(-) enantiomer. Cephalon Pharma Company produces it. Armodafinil was approved by the food and drug administration in June 2007. Since Armodafinil comes from Modafinil, it is more potent when compared to its generic version. However, the Armodafinil online price in the USA is comparatively lower than Modafinil. 

Armodafinil vs Modafinil- Notable Similarities 

Armodafinil vs Modafinil similarties

Apart from similar uses, there are a few other similarities between Modafinil and Armodafinil. 

Low risk of dependence- Armodafinil and Modafinil are non-narcotic Schedule IV drugs with a low risk of abuse and dependency. 

Controlled substance- They are both considered a controlled substance and is available with a prescription. 

Mechanism of action- Armodafinil and Modafinil function in the brain's hypothalamus region. They both enhance wakefulness by interacting with the CNS and increasing the level of dopamine and histamine in the brain. 

Performance- Both Modafinil and Armodafinil have a 30 minutes onset of action. 

Interaction with Food- The intake of food with Armodafinil and Modafinil can delay the onset of action of the Nootropics by 1 to 2 hours. However, it does not affect the bioavailability of the drug. 

Main differences between Armodafinil and Modafinil?

In this debate on Armodafinil vs. Modafinil, both the Nootropics are seen to possess a few striking differences. 

FACTORS

ARMODAFINIL

MODAFINIL

Dosage

The dose that experts usually recommend is Armodafinil 150 mg.

The Modafinil dose that is advisable for your usage is 200mg.

Brand 

Armodafinil is available under the brand name Waklert and Artvigil. 

The brand names of Modafinil are Modalert, Provigil, and Modvigil. 

Action Time 

The action of Armodafinil lasts for about 18 hours.

Modafinil acts for about 16 hours in the person.

Armodafinil vs Modafinil- Medical benefits 

Condition

Armodafinil 150mg

Modafinil 200mg

Shift work sleep disorder

Yes

Yes

Narcolepsy

Yes

Yes

Obstructive sleep apnea

Yes

Yes

Mental health issues (depression, ADHD)

Off-label

Off-label

Multiple sclerosis-related fatigues

Off-label

Off-label

Cognition enhancement

Off-label

Off-label

Cancer-related fatigue

Off-label

Off-label

Modafinil vs Armodafinil- Coverage and cost comparison 

The cost of both Armodafinil and Modafinil differs depending on the pharmacy. Moreover, the package and strength of Nootropics are also important. In addition, they differ in their generic and brand versions. 

Insurance plans cover the cost of both Armodafinil and Modafinil. 

 

Modafinil

Armodafinil

Coverage by Insurance

Yes

Yes

Coverage by Medicare

Yes

Yes

Standard dose

Modafinil 200mg

Armodafinil 150mg

Price at Healthmatter

$1.3

$1.6

Additional discounts at Healthmatter

Extra free pills on first order with additional offers on festive seasons

Extra free pills on first order with additional offers on festive seasons

Shipping fee

Free shipping

Free shipping

Coupon

Available

Available

Common side effects of armodafinil and modafinil

Armodafinil vs Modafinil side effects

Side effects of Modafinil and Armodafinil are mild with no severe or life-threatening symptoms. However, Modafinil has a higher chance of causing side effects than Armodafinil. Adverse effects may occur if overdosed or if administered improperly. 

Adverse effects

Armodafinil frequency

Modafinil frequency

Insomnia

5%

5%

Headache

17%

34%

Back pain

No

7%

Nausea

7%

11%

Dry mouth

4%

4%

Indigestion

2%

5%

Decreased appetite

1%

4%

Nervousness

1%

7%

Dizziness

5%

5%

This is not a complete list of all the possible side effects of Armodafinil and Modafinil. Depending on the cause and the dose taken, the severity of the condition may vary. In addition, if the condition persists or gets worsens with time, it is advisable to consult a doctor. 

Armodafinil vs. Modafinil- Drug interactions

The intake of other medications and supplements with Modafinil and Armodafinil can cause drug interactions resulting in lower efficacy and potency. Check with your doctor before administering Armodafinil and Modafinil if you are undergoing other treatments. 

The common medicines that interact with Modafinil and Armodafinil are-

Armodafinil

Modafinil

Amphetamine

Atogepant

Chloramphenicol

Axitinib

Fentanyl

Belzutifan

Lumateperone

Entrectinib

Methadone

Levomethadyl

Butorphanol

Finerenone

Apart from the medicines listed here, Armodafinil and Modafinil can interact with numerous other medications. Armodafinil is identified to interact with 433 drugs, whereas, Modafinil can interact with about 449 medicines. 

Preventive measures of Armodafinil and Modafinil

Modafinil and Armodafinil are safe for use and are commonly recommended to all people. However, under certain conditions, one should refrain from using Armodafinil and Modafinil as they can increase the chances of experiencing side effects. 

Factors

Armodafinil  and Modafinil warnings

Age

The use of Armodafinil 150mg and Modafinil 200mg is not recommended for people above the age of 65 years and below 17 years. Such people must take the Nootropic under the supervision of a physician. 

Pregnancy and lactating women

Armodafinil and Modafinil are Category C drugs. Therefore it should not be taken during pregnancy and breastfeeding without consulting a doctor. 

History of abuse

People with a history of chemical abuse should always take Modafinil or Armodafinil without a valid medical prescription. As such people are vulnerable to experiencing abuse and addiction. 

Health disorders

Users with kidney, liver, and heart issues should not take Modafinil and Armodafinil doses without a prescription. 

Alcohol interaction

The intake of Armodafinil and Modafinil with alcohol can make the person tolerant. In addition, it can develop signs of nausea, dizziness, and drowsiness. Moreover, it can also cause lower bp.

Armodafinil vs. Modafinil - The Final Verdict

We believe both Armodafinil and Modafinil are very effective and potent in helping achieve health benefits. They have both excelled in achieving both prescription and off-label uses. They also have similar onset of action. Thus, making it hard for one to choose the right one. People looking for a Nootropic with a longer time of action can choose Armodafinil 150mg. However, the price of Modafinil is lower, so people on a budget can buy Modafinil 200 mg. 


FAQ's

Obstructive sleep apnea is a sleep disorder that can stop a person from getting enough sleep at night. Patients with obstructive sleep apnea can also lose their active energy due to a lack of sleep. Smart drugs like Modafinil or Armodafinil cannot cure these conditions. These smart drugs can help patients with obstructive sleep apnea to stay active during working hours. Both the Nootropics are equally effective and potentially manage Obstructive sleep apnea.

Shift work sleep disorder is a sleeping disorder in people who work different shifts. The normal sleep cycle makes it common to feel tired, low, and sleepy at night. Taking Modafinil or Armodafinil dosage 30 minutes before starting their work shift can help them work and function better.

Both Armodafinil and Modafinil are formulated with similar active compounds; therefore, taking them together may increase the risk of experiencing side effects.

No, Armodafinil and Modafinil do not show up on drug tests.


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Disclaimer: We do not provide any medical advice.

The contents of Healthma are for informational purpose only and is taken by a thorough evaluation of research papers and Journals. We do not provide professional medical advice, treatment, or diagnosis. We advise all readers to consult a physician before consuming any medication mentioned on the website.