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Armodafinil vs. Modafinil- If you are struggling in choosing between the two most effective Nootropics, we have you covered.
Both Armodafinil and Modafinil are prescription medicines and are approved by the FDA for treating excessive daytime sleepiness. They are also well-known for their numerous off-label benefits.
Choosing between their therapeutic benefits and establishing which is better can be very tedious, so let us have a better insight on Armodafinil and Modafinil and establish the right one for you.
Armodafinil vs Modafinil- An overview of the Nootropics
Modafinil 200mg:
Modafinil is available under the brand name Provigil, Modvigil, and Modalert. The high efficacy of the Modafinil brand makes the comparison between Modalert vs Modvigil common. In addition, it is very effective in reducing the sign of excessive daytime sleepiness arising from sleep disorders such as shift work sleep disorder, narcolepsy, and obstructive sleep apnea. The off-label uses of Modafinil include enhancing cognition in people. Modafinil 200 mg is approximately $1 per pill, making it affordable.
Armodafinil 150mg:
Armodafinil is an enantiopure compound of Modafinil. Moreover, this Nootropic contains Modafinil's (R)-(-) enantiomer. Cephalon Pharma Company produces it. Armodafinil was approved by the food and drug administration in June 2007. Since Armodafinil comes from Modafinil, it is more potent when compared to its generic version. However, the Armodafinil online price in the USA is comparatively lower than Modafinil.
Armodafinil vs Modafinil- Notable Similarities
Apart from similar uses, there are a few other similarities between Modafinil and Armodafinil.
Low risk of dependence- Armodafinil and Modafinil are non-narcotic Schedule IV drugs with a low risk of abuse and dependency.
Controlled substance- They are both considered a controlled substance and is available with a prescription.
Mechanism of action- Armodafinil and Modafinil function in the brain's hypothalamus region. They both enhance wakefulness by interacting with the CNS and increasing the level of dopamine and histamine in the brain.
Performance- Both Modafinil and Armodafinil have a 30 minutes onset of action.
Interaction with Food- The intake of food with Armodafinil and Modafinil can delay the onset of action of the Nootropics by 1 to 2 hours. However, it does not affect the bioavailability of the drug.
Main differences between Armodafinil and Modafinil?
In this debate on Armodafinil vs. Modafinil, both the Nootropics are seen to possess a few striking differences.
|
FACTORS |
ARMODAFINIL |
MODAFINIL |
|---|---|---|
Dosage |
The dose that experts usually recommend is Armodafinil 150 mg. |
The Modafinil dose that is advisable for your usage is 200mg. |
Brand |
Armodafinil is available under the brand name Waklert and Artvigil. |
The brand names of Modafinil are Modalert, Provigil, and Modvigil. |
Action Time |
The action of Armodafinil lasts for about 18 hours. |
Modafinil acts for about 16 hours in the person. |
Armodafinil vs Modafinil- Medical benefits
|
Condition |
Armodafinil 150mg |
Modafinil 200mg |
|---|---|---|
|
Shift work sleep disorder |
Yes |
Yes |
|
Narcolepsy |
Yes |
Yes |
|
Obstructive sleep apnea |
Yes |
Yes |
|
Mental health issues (depression, ADHD) |
Off-label |
Off-label |
|
Multiple sclerosis-related fatigues |
Off-label |
Off-label |
|
Cognition enhancement |
Off-label |
Off-label |
|
Cancer-related fatigue |
Off-label |
Off-label |
Modafinil vs Armodafinil- Coverage and cost comparison
The cost of both Armodafinil and Modafinil differs depending on the pharmacy. Moreover, the package and strength of Nootropics are also important. In addition, they differ in their generic and brand versions.
Insurance plans cover the cost of both Armodafinil and Modafinil.
|
|
Modafinil |
Armodafinil |
|---|---|---|
|
Coverage by Insurance |
Yes |
Yes |
|
Coverage by Medicare |
Yes |
Yes |
|
Standard dose |
Modafinil 200mg |
Armodafinil 150mg |
|
Price at Healthmatter |
$1.3 |
$1.6 |
|
Additional discounts at Healthmatter |
Extra free pills on first order with additional offers on festive seasons |
Extra free pills on first order with additional offers on festive seasons |
|
Shipping fee |
Free shipping |
Free shipping |
|
Coupon |
Available |
Available |
Common side effects of armodafinil and modafinil
Side effects of Modafinil and Armodafinil are mild with no severe or life-threatening symptoms. However, Modafinil has a higher chance of causing side effects than Armodafinil. Adverse effects may occur if overdosed or if administered improperly.
|
Adverse effects |
Armodafinil frequency |
Modafinil frequency |
|---|---|---|
|
Insomnia |
5% |
5% |
|
Headache |
17% |
34% |
|
Back pain |
No |
7% |
|
Nausea |
7% |
11% |
|
Dry mouth |
4% |
4% |
|
Indigestion |
2% |
5% |
|
Decreased appetite |
1% |
4% |
|
Nervousness |
1% |
7% |
|
Dizziness |
5% |
5% |
This is not a complete list of all the possible side effects of Armodafinil and Modafinil. Depending on the cause and the dose taken, the severity of the condition may vary. In addition, if the condition persists or gets worsens with time, it is advisable to consult a doctor.
Armodafinil vs. Modafinil- Drug interactions
The intake of other medications and supplements with Modafinil and Armodafinil can cause drug interactions resulting in lower efficacy and potency. Check with your doctor before administering Armodafinil and Modafinil if you are undergoing other treatments.
The common medicines that interact with Modafinil and Armodafinil are-
|
Armodafinil |
Modafinil |
|---|---|
|
Amphetamine |
Atogepant |
|
Chloramphenicol |
Axitinib |
|
Fentanyl |
Belzutifan |
|
Lumateperone |
Entrectinib |
|
Methadone |
Levomethadyl |
|
Butorphanol |
Finerenone |
Apart from the medicines listed here, Armodafinil and Modafinil can interact with numerous other medications. Armodafinil is identified to interact with 433 drugs, whereas, Modafinil can interact with about 449 medicines.
Preventive measures of Armodafinil and Modafinil
Modafinil and Armodafinil are safe for use and are commonly recommended to all people. However, under certain conditions, one should refrain from using Armodafinil and Modafinil as they can increase the chances of experiencing side effects.
|
Factors |
Armodafinil and Modafinil warnings |
|---|---|
Age |
The use of Armodafinil 150mg and Modafinil 200mg is not recommended for people above the age of 65 years and below 17 years. Such people must take the Nootropic under the supervision of a physician. |
Pregnancy and lactating women |
Armodafinil and Modafinil are Category C drugs. Therefore it should not be taken during pregnancy and breastfeeding without consulting a doctor. |
History of abuse |
People with a history of chemical abuse should always take Modafinil or Armodafinil without a valid medical prescription. As such people are vulnerable to experiencing abuse and addiction. |
Health disorders |
Users with kidney, liver, and heart issues should not take Modafinil and Armodafinil doses without a prescription. |
Alcohol interaction |
The intake of Armodafinil and Modafinil with alcohol can make the person tolerant. In addition, it can develop signs of nausea, dizziness, and drowsiness. Moreover, it can also cause lower bp. |
Armodafinil vs. Modafinil - The Final Verdict
We believe both Armodafinil and Modafinil are very effective and potent in helping achieve health benefits. They have both excelled in achieving both prescription and off-label uses. They also have similar onset of action. Thus, making it hard for one to choose the right one. People looking for a Nootropic with a longer time of action can choose Armodafinil 150mg. However, the price of Modafinil is lower, so people on a budget can buy Modafinil 200 mg.