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Armodafinil in the treatment of Obstructive Sleep Apnea

Armodafinil in the treatment of Obstructive Sleep Apnea

Last updated on 27 Apr, 2024

Armodafinil is a nootropic that helps treat symptoms associated with Obstructive Sleep Apnea. It starts it’s working within 30 minutes after consumption. 

Armodafinil 150 mg is the standard recommended dosage for patients with Obstructive Sleep Apnea. 


Armodafinil, with its strong stimulating effects, has proven to be an effective solution for the treatment of excessive daytime sleepiness. 

Here, in this blog, we will discuss in detail,  the effectiveness of Armodafinil for Obstructive Sleep Apnea. 

What Is Armodafinil?

Armodafinil is a prescription medication that is the R-enantiomer of Modafinil and belongs to the Eugeroic group (a group that promotes wakefulness). 

The three basic prescription uses of Armodafinil are narcolepsy, obstructive sleep apnea, and shift work disorders. 

The FDA approved the Schedule IV drug in 2007. It is sold under different brands like- Waklert, Artvigil, and Nuvigil.

Obstructive Sleep Apnea And Its Symptoms 

Obstructive sleep apnea is a sleep ailment that is seen in all age groups. It is characterized by episodes of complete or partial collapse of the airway in association with a decrease in oxygen saturation or arousal from sleep. This results in fragmented sleep, disturbing the natural sleep cycle. 

-Symptoms of Obstructive Sleep Apnea

  • Excessive daytime sleepiness

  • Trouble focussing during the day.

  • Decreased Interest in sex.

  • Frequent mood changes

  • Waking up during the night and gasping or choking

  • Morning headaches [2].

What Is The Best Medication For Sleep Apnea?

Armodafinil is recommended as one of the best nootropics or medications for obstructive sleep apnea. 

According to a meta-analysis made by Yi-Chun Kuan and others, Armodafinil, as a nootropic, significantly improved subjective and objective daytime sleepiness [3]. 

Another study made by JeD E Black and others found that Armodafinil is an effective and well-tolerated drug solution for patients with long-term treatment associated with Obstructive Sleep Apnea [4]. 

People are recommended to buy Armodafinil for obstructive sleep apnea for not more than three weeks of use. Long-term use of this medication must be done under the supervision of a doctor. 

How Does Armodafinil Help In Obstructive Sleep Apnea?

Armodafinil works in the brain by increasing the levels of neurotransmitters like serotonin, norepinephrine, orexin, histamine, and dopamine that decreases the levels of GABA (neurotransmitter promoting sleepiness), which as a result, promotes wakefulness in people suffering from Obstructive Sleep Apnea. 

How Long Is Armodafinil Effective For Obstructive Sleep Apnea?

Armodafinil is a medication that starts working within 30 minutes after its administration.

The half-life of Armodafinil is 12-15 hours (the amount of time required by medicine to reduce by half ). Hence, the effects last for about 12-15 hours. 

Generally, a medication requires 4-5 half-lives to be completely removed from the system.  Therefore, Armodafinil requires about 60-75 hours to be alleviated from the system completely. 

Armodafinil Dosage For Obstructive Sleep Apnea


Armodafinil 150 mg is the standard recommended dosage of Modafinil for Obstructive Sleep Apnea. However, the dosage might vary from patient to patient depending on certain factors like age and health conditions (kidney or liver dysfunction).  

The recommended time for taking Armodafinil for Obstructive Sleep Apnea is in the morning in order to avoid Insomnia. 

The maximum recommended dosage for Armodafinil is 500mg/day (250 each) [5]. 

The use of Armodafinil is recommended for up to 2 weeks, followed by a regular dosage. 

How To Use Armodafinil For Obstructive Sleep Apnea?

There are six simple steps to be followed while using Armodafinil for Obstructive Sleep Apnea-

1. Take the medication as a whole with a glass of water. 

2. You should not crush or chew the tablet. 

3. Avoid the consumption of Alcohol while taking the medication. 

4. Avoid the medication if you’re pregnant.

5. You should not take the medication, at the stage of breast-feeding. This might harm your baby. 

6. Take the tablet at the same time of the day for better effectiveness. 

Customer Reviews Of Armodafinil For Obstructive Sleep Apnea

Armodafinil has an average rating of 7.7 out of 10 on an overall total of 51 reviews for the treatment of Obstructive Sleep Apnea on the website

“I was suffering from Obstructive Sleep Apnea for 10 years. I was suffering from a terrible headache after I woke up. Armodafinil brought my life back after 10 years”, stated a customer on the website

“Armodafinil has turned my world into a different one. It’s been 3 years I have been using the medication, and it has worked like magic without any side effects”, a customer states on the website 

Armodafinil In The Treatment Of Obstructive Sleep Apnea: Conclusion

Armodafinil is an excellent treatment option for excessive sleepiness associated with Obstructive sleep apnea. To get the most out of this drug, it is always advised to consult your doctor first.


Armodafinil and Modafinil are considered the best stimulants for Obstructive Sleep Apnea.

Armodafinil 150mg is the standard recommended dosage for Sleep Apnea.

Armodafinil is 1.33% more potent than Modafinil, as Armodafinil 150mg was more comparable to Modafinil 200 mg.

Yes, Armodafinil is safe to take with very minimal side effects- dizziness, drowsiness, headache, vomiting, etc.

Armodafinil should be taken once every day for better results.


  1. Sleep Apnea, Mayoclinic. 

  2. Obstructive Sleep Apnea, Mayoclinic

  3. Effects of Modafinil and Armodafinil in Patients With Obstructive Sleep Apnea: A Meta-analysis of Randomized Controlled Trials, NCBI

  4. The long-term tolerability and efficacy of armodafinil in patients with excessive sleepiness associated with treated obstructive sleep apnea, shift work disorder, or narcolepsy: an open-label extension study, NCBI

  5. Armodafinil (oral route), Mayo Clinic.


Disclaimer: We do not provide any medical advice.

The contents of HealthMatter are for informational purpose only and is taken by a thorough evaluation of research papers and Journals. We do not provide professional medical advice, treatment, or diagnosis. We advise all readers to consult a physician before consuming any medication mentioned on the website.