How to sleep on Modafinil | The Complete Guide 2022

How to sleep on Modafinil

Last updated on July 20th, 2022

Do you have trouble sleeping after administering Modafinil? If yes, it’s time to change things up. This comprehensive guide will show you how to sleep on Modafinil to help you or your loved one with insomnia.

Modafinil is a powerful smart drug that works wonders for many people to increase productivity and boost general health. One common mistake is ingesting it right before bed. A single dose of this Nootropic keeps you awake for 12-15 hours. Thus, depicting that the Nootropic does not work well with ensuring a good night’s sleep. This comprehensive study helps people get a better insight into taking Modafinil dosage without compromising their regular sleep schedule.


How does Modafinil work to regulate sleep?

How to sleep on Modafinil

Before discussing Modafinil, let’s first know what insomnia is and how it impacts your sleep.

Having problems sleeping and staying asleep is a symptom of insomnia. The disorder could either be acute or permanent (chronic). And it could come and go.

Modafinil has been attracting a lot of attention recently because of its effects, which include promoting wakefulness. It is an effective solution for treating excessive daytime sleepiness in people with medical conditions like narcolepsy, sleep apnea, and idiopathic hypersomnia. Nootropic helps regulate sleep in people by adopting these two methods [1]:


Reduce EDS related to epileptic seizures

Excess drowsiness, also referred to as excessive daytime sleepiness (EDS), is a common symptom of epileptic seizures. However, in some cases, taking antiepileptic drugs may also cause EDS.

Modafinil has Anticonvulsant properties, allowing it to restrict brain activity as necessary, lowering the frequency of seizure events. According to experts, Modafinil has an advantage over most well-known drugs due to its low potential for abuse. 


Prevent Dopamine reuptake

Modafinil is a mild dopamine reuptake inhibitor (DRI). Conditions like narcolepsy restrict dopamine production and often make people drowsy. It prevents the reuptake of the hormone, thus enhancing its secretion in the body. 

Numerous research emphasizes the importance of dopamine in wakefulness. For starters, it prevents the pineal gland from secreting norepinephrine, a necessary step in the production of melatonin, which controls your sleep cycle. 

The DRI (Dopamine reuptake inhibitor) rate for Modafinil ranges between 51.4 percent for a 200 mg dose and 56.9 percent for a 300 mg dose, according to a study conducted in 2014 and published in the International Journal of Neuropsychopharmacology.


How does Modafinil hinder sleep in healthy and sleep-deprived individuals?

How to sleep on Modafinil

Total and partial sleep deprivation are the two categories of sleep deprivation. Total sleep deprivation occurs when a person doesn’t sleep throughout the normal sleep/wake cycle.”Partial sleep deprivation” refers to a sleepless or disrupted night.

How individuals respond to sleep deprivation is variable and depends on several factors, including age, previous sleep amount, and sleep distribution.

Modafinil prevents gamma-aminobutyric acid, essential for controlling the “sleepiness” phase of the sleep-wake cycle. However, Modafinil helps produce histamine, glutamate, and norepinephrine, which support the sympathetic nervous system for enhancing wakefulness [2].

Interestingly, Modafinil does not affect melatonin production. It is a hormone that is produced at night to make people feel sleepy. 

It is to be kept in mind that Modafinil’s effect can last up to 18 hours after taking it. Taking Modafinil before bed is a terrible idea as 200mg has a half-life of 12-15 hours (i.e., the amount of time needed for 50% of the drug removal from your bloodstream).

  “Modafinil takes five half-lives to be removed from the body as off up to 97%. “

Because a drug’s clearance follows a logarithmic function, doubling the dose will often increase the half-life duration.


The Role of Modafinil in Treating Sleep Disorders

How to sleep on Modafinil

The ability to induce wakefulness is one of Modafinil’s qualities, which has recently drawn interest in sleep medicine. It makes Modafinil a potentially effective treatment option for excessive diurnal somnolence (EDS), which can occur together with sleep disorders such as narcolepsy, sleep apnea, idiopathic hypersomnolence, and other illnesses marked by inadequate sleep quantity and quality.

Modafinil helps people to stay awake; it is neither chemically nor pharmaceutically related to other common CNS stimulants that help people with hypersomnia, like amphetamine or methylphenidate.

People can choose to buy Modafinil 200mg over other medications as it is far more site-specific than other CNS stimulants. Its ability to promote wakefulness depends on the a1-adrenergic system (necessary for neurotransmission and sympathetic nervous system) working correctly.


Tips to regulate a normal sleep cycle on Modafinil

How to sleep on Modafinil

Modafinil and sleep: is it possible? Absolutely! 

Research has discovered numerous effective methods to offset Modafinil’s effects. Incorporating them each time you take a Nootropic will help you sleep on Modafinil.


Take your dose of Modafinil early

It is one of the essential tips on how to take Modafinil. The earlier you start taking Modafinil, the higher your chances are of falling asleep at a reasonable hour.

You have a decent probability of falling asleep before midnight if you take Modafinil before 10 am.

Research says that the best benefits came from taking Modafinil before 8:30 am.

Even though Modafinil remains in your system for 12 to 15 hours, it’s enough to make it difficult to fall asleep.

Additionally, unless you are determined to pull an all-nighter, DO NOT take Modafinil before bed. 


Maintain good sleeping habits

Before adjusting your Modafinil dosage, make sure you have lifestyle patterns that naturally cause you to feel exhausted, enabling you to fall asleep.  

These few practices are essential to achieving a restful night’s sleep:

  • Make sure to consume 2-4 liters of water during the day to prevent dehydration, which can impair your ability to sleep.
  • Before going to bed, ensure all lights and electronic devices are off. That means keeping your smartphone away from your reach.
  • Try something to take your mind off things, like reading a novel.
  • Set a wake-up alarm for the following morning.
  • Exercise vigorously (at least 3 hours before bed) will increase your sleep quality and speed up your ability to fall asleep.
  • Take a lukewarm bath or shower 60 to 90 minutes before bed.
  • Avoid consuming meals and beverages that may prolong the effects of Modafinil, such as grapefruit juice (due to inhibiting the enzyme that metabolizes Modafinil).

Try one strategy at a time to test if it will improve your regular sleeping patterns. Before using Modafinil, optimize your sleep routine for the most significant outcomes.


Reduce your Modafinil intake every day

The daily recommended dose for Modafinil is 200mg; do not exceed more than that.

In some cases, studies discovered that lowering their daily Modafinil dosage to 50 mg was the only way to prevent remaining alert past 9 o’clock.

However, we do not advise spreading your Modafinil dosage throughout the day.

Studies have demonstrated that split dosages of 200 mg of Modafinil (i.e., 100 mg in the morning and 100 mg in the afternoon) significantly prolong wakefulness into the late evening. 


Avoid the use of other stimulants

It could be notably harder to sleep at a regular hour if you combine Modafinil with other stimulants like caffeine.

Caffeine has a 6-hour half-life, so it is best to avoid consumption past 4 pm to avoid feeling awake before bed. For optimum results, we suggest preventing the intake of coffee after 2:00 pm.


Reduce the number of times you take Modafinil in a week

Try not to take Modafinil more than 1-3 days per week to prevent long-term disruption of a regular sleeping routine.

Additionally, to ensure you can take Modafinil and get a good night’s sleep, we advise spaced dosing evenly throughout the week (i.e., one dose on Monday, one dose on Wednesday, and one dose on Friday).

Modafinil may cover up your weariness and other signs of severe sleep deprivation if you take it more frequently than this. It ” helps you to stay awake instead of making you awake.” However, it is NOT a replacement for getting 7-8 hours of unbroken sleep each night.


Explore the use of pharmaceutical or over-the-counter sedatives

We are not recommending that you use these sleep aids, some of these could need a prescription from a doctor, and it is unknown how they would interact with Modafinil:

  • Zolpidem ( used to counteract Modafinil’s wakefulness-promoting effects) 
  • Anti-histamine medications (Doxylamine, Cetirizine, Mirtazapine, Hydroxyzine)
  • Glycine
  • Melatonin
  • Magnesium

The amount and time will change with each sleep study. However, several users claim that taking them 1-2 hours before bed produces the best outcomes.


Try natural alternatives

Taking natural sleep aids will assist you in getting the “sleep” you seek if you want to ensure that Modafinil and insomnia never coexist.

Try mixing the following for better results- 

  • Two servings of cherry juice 
  • 70 mg of CBD oil with 600 mg of ashwagandha 
  • A cup or two of chamomile tea

We strongly advise using cannabinoid (CBD) oil if you only use one ingredient from these four. This compound can help indirectly improve sleep by reducing chronic pain. It may also treat excessive daytime sleepiness and reduce morning grogginess.

Users taking this cocktail 1-2 hours before bed can help you get some revitalized sleep that will leave you feeling refreshed and awake in the morning. 


Insomnia and Modafinil | Our final verdict

If you have tried every suggestion in this article and are still unable to sleep, your best option is to completely stop taking Modafinil for a few days to observe how it affects your night’s sleep.

We advise taking these steps because when drug users inquire, “Can you sleep on Modafinil?” they mean to know if they can sleep while Modafinil is still active in their system.

Although many users claim to have woken up frequently throughout the night, it is a conceivable justification why we do not recommend using Modafinil past midnight unless it is essential.

If your sleep schedule doesn’t improve on its own, you can be experiencing insomnia caused by another illness.

Please consult a qualified medical professional so you can identify the root of your sleeplessness and take the appropriate action to address it.

Above all, remember that every individual’s reaction to Modafinil varies significantly. Several environmental elements can change how Modafinil affects you.

Consequently, one user’s experience may not be representative of your own when learning how to sleep on Modafinil.


Faq on How to sleep on Modafinil

Can you sleep with Modafinil?

Yes, you can sleep on Modafinil. Maintaining a regular sleep cycle and following a doctor’s guidance while administering the Nootropic will ensure you can sleep well after taking the Nootropic. 

How long does Modafinil keep you awake?

A single dose of Modafinil keeps you awake for 12-15 hours. 

How long does 100mg of Modafinil last?

A 100mg of Modafinil last between 12-15hours.

Should I take Modafinil before sleep?

Taking Modafinil before bed is a bad idea as 200mg has a half-life of 12-15 hours (i.e., the amount of time needed for 50% of the drug to eliminate from your bloodstream). Therefore, if you need to get to bed early, don’t take more than 200 mg of Modafinil.

How long does Modafinil last

A single dose of Modafinil keeps you awake for 12-15 hours. Thus, depicting that Modafinil ensures awake full restoring sleep.



The content here is informative and should not be taken as professional medical advice or diagnosis. We request our readers to consult a doctor before taking any medications mentioned here. 



  1. How Does Modafinil Work To Regulate Sleep?, alaskasleep
  2. How to Sleep on Modafinil | A-Z Guide, Modafinil