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March 11, 2022 
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Armodafinil vs. Adderall is an evaluation of its uses, benefits, and safety profile. Armodafinil is a safer option than Adderall, with fewer side effects and a lower risk of dependency. It is also a more affordable choice of stimulant than Adderall.
Wondering which among “Armodafinil vs. Adderall” is a better option? We have you covered.
Armodafinil and Adderall are two significant nootropics known for their prescription and off-label benefits. Both stimulants are noted to offer similar benefits, thus making it hard for people to decide.
This comprehensive guide will outline every crucial product detail to help you find the right Nootropic.
Armodafinil Vs. Adderall- An overview
Armodafinil is an effective Nootropic that can help us enhance wakefulness. Moreover, Armodafinil is prescribed for Excessive Sleep Disorders associated with Narcolepsy, Sleep Apnea, and Shift Work Sleep Disorder [1].
Adderall is a stimulant designed to treat the sleep disorder such as Narcolepsy and Attention deficit hyperactivity disorder (ADHD). It contains amphetamines which differ from most Nootropics. In addition, people now use this stimulant to stay focused.
|
|
Armodafinil |
Adderall |
|---|---|---|
|
Dosage |
|
The dosages of Adderall are two or three times a day. Therefore, start taking your dosage just after waking up in the morning. Similarly, continue taking it during the day by taking a gap of 4 to 6 hours. Moreover, take it orally without breaking it. |
|
Half-life |
Approximately 15 hours |
Around 9 to 14 hours |
|
Drug class |
CNS stimulant |
CNS stimulant |
|
Available dosage forms |
|
|
|
CSA schedule |
Armodafinil is a medicine that has a low potential for abuse. Moreover, in the United States, it is accepted for medical use. It falls under the Schedule IV drug list. It has a lower or negligible risk of physical or psychological dependence. |
Adderall is a schedule II medicine that has a high potential for abuse. However, it is currently accepted for medical use in the United States but with several restrictions. Therefore, if you abuse it, it may lead you to suffer from physical and psychological dependence. |
A Comparison Of Armodafinil And Adderall Benefits
While the Armodafinil vs. Adderall comparison can be difficult as they portray similar benefits, they have prevalent advantages. Some of the comparable benefits of Armodafinil and Adderall are listed below.
Armodafinil Benefits-
- Enhanced focus and Cognition
Armodafinil can help people stay focused for hours with improved creativity, concentration, and memory. It is also associated with improving the thinking and decision-making ability of users.
- Not an amphetamine-based Nootropic
Unlike Adderall, Armodafinil doesn't contain amphetamine that helps prevent certain side effects of the stimulant, such as anxiety and excessive sweating.
- Longer half-life
The elimination half-life of Armodafinil (15 hours) is longer compared to Modafinil (12 hours) and Adderall (12 hours). It makes Armodafinil effective compared to Adderall.
- Fewer side effects
In comparison to Adderall, the side effects of Armodafinil are less frequent and severe. Many users report not experiencing any adverse effects from Armodafinil.
- Lower possibility of sleep disturbance
Adderall can be hard to sleep on; however, if Armodafinil is taken correctly, it does not affect a person's sleep cycle.
Adderall Benefits
- Intensity
Adderall is one of the most intense stimulants available. It is too strong to fail and can guarantee to get almost all jobs done.
- Cause High
Adderall is formulated with amphetamines that can make you feel high. It will also induce a strong sense of happiness, focus, and productivity.
- High energy level
Being an amphetamine-based stimulant, Adderall is a more potent energy booster compared to Armodafinil.
Artvigil Vs. Adderall - Off-Label And Prescription Use
The FDA primarily approves Armodafinil for treating excessive daytime sleepiness associated with obstructive sleep apnea, Narcolepsy, and shift work sleep disorder. Likewise, Adderall is approved by the FDA for treating Narcolepsy [2].
|
Condition |
Armodafinil |
Adderall |
|---|---|---|
|
ADHD |
Off-label |
Yes |
|
Narcolepsy |
Yes |
Yes |
|
Cognition |
Off-label |
Off-label |
|
Armodafinil and Adderall for Shift work sleep disorder |
Yes |
Off-label |
|
Obstructive sleep apnea |
Yes |
Off-label |
Armodafinil Vs. Adderall- The Notable Differences
- Active ingredient-
Armodafinil is the generic version. It contains 150mg of Armodafinil compound in its formulation. In comparison, Adderall has a combination of dextroamphetamine and amphetamine salts.
- Formulations
Armodafinil and its brand versions are available as oral tablets in the strengths of 50mg, 150mg, 200mg, and 250mg. Adderall, on the other hand, is available as oral tablets and in extended-release capsules. It comes in the strengths of 5mg, 10mg, 15mg, 20mg, 25mg, and 30mg.
- Risk of abuse
Armodafinil is a Schedule IV drug, whereas Adderall is a Schedule II medication. It indicates Armodafinil has a lower risk of abuse compared to Adderall.
- Age restrictions
Armodafinil is restricted to people of 17 years and above. However, Adderall can be taken by adults and children of 3 years and more.
Armodafinil Vs. Adderall- Comparison Of Cost And Coverage
Armodafinil is often covered by most insurance policies, whereas Adderall is not since it is a brand-name drug. Adderall can cost $315 for 30 and 20 mg tablets. However, the cost of Armodafinil is $1.60 per pill at Healthmatter [2].
|
|
Armodafinil |
Adderall |
|---|---|---|
|
Covered by Insurance |
Yes |
Often No |
|
Covered by Medicare Part D |
Yes |
No (only the generic) |
|
Quantity |
100 to 400 pills |
30 pills of 20 mg tablets |
Pharmacodynamic Interactions Of Adderall Vs. Armodafinil
Armodafinil and Adderall can interact with many of the same drugs. Armodafinil is identified to interact with 432 medications, whereas Adderall is known to interact with 181 drugs.
Armodafinil is known to cause 16 major, 230 moderate, and 186 minor interactions. On the other hand, Adderall can cause 36 major, 135 moderate, and nine minor interactions [3] [4].
Even though Armodafinil is prone to drug interactions, Adderall has a higher risk of causing a severe effect on the user.
|
Drug Class |
Armodafinil |
Adderall |
|---|---|---|
|
Monoamine oxidase inhibitors (MAOIs) |
Yes |
Yes |
|
Hormonal contraceptives |
Yes |
No |
|
Antihypertensives |
No |
Yes |
|
Proton pump inhibitors (PPIs) |
Yes |
Yes |
|
Serotonergic drugs |
No |
Yes |
|
Immunosuppressants |
Yes |
No |
Mixing Armodafinil And Adderall- Is It A Wise Decision?
Many people take Armodafinil and Adderall simultaneously in the hope of getting higher brain activity and doubling up their functioning. But is this interaction safe?
Armodafinil can interact individually with the two active compounds of Adderall.
Mixing Adderall and Armodafinil can trigger overstimulation that can result in adverse effects. Such people are more likely to experience nausea, anxiety, twitchiness, palpitation, and irritability [5].
Side Effects Of Adderall And Armodafinil
Adderall cause significantly more side effects than Armodafinil, which is a well-tolerated drug. Thus, Armodafinil has a lower poteny for causing side effects.
The severity of the adverse effects of Adderall is also higher compared to Armodafinil [6] [7].
|
Armodafinil |
Adderall |
|---|---|
|
Headache |
Fever |
|
Nausea |
Nausea |
|
Weight loss |
Muscle spasm |
|
Diarrhea |
Addiction |
|
Insomnia |
When mixed with alcohol, it can cause a heart attack. |
|
Hypertension |
Diarrhea |
|
|
High blood pressure. |
|
|
Muscle twitching. |
Note - This is not the complete list of all the possible side effects of Adderall and Armodafinil. Before taking these nootropics, consult your doctor and talk about the possible side effects of them.
Nuvigil vs. Adderall- Warning And Precaution
The use of Armodafinil and Adderall is contradicted in people with kidney, liver, and heart issues. Administering these stimulants can increase the risk of cardiac disorder and elevate heart rate, blood pressure, and stroke.
Adderall and Armodafinil use can also increase the risk of psychiatric events such as depression, hallucinations, aggression, mania, and delusional thinking. The possibility of these is higher in people with a history of mental health disorders.
In rare cases, these stimulants can cause allergic reactions and severe rashes like Stevens-Johnson syndrome.
Apart from these, the use of Adderall can cause other health risks such as visual disturbances, growth suppression (in children), and serotonin syndrome.
Armodafinil vs Adderall- Our Final Verdict
Armodafinil and Adderall are both nootropics that can help us stay active. However, if you ask us which of these two is better, it would undeniably be Armodafinil.
Armodafinil is a safer option than Adderall as it is a Schedule IV drug with lower dependency. It is also associated with minor and less frequent side effects than Adderall.
The price of Armodafinil is lower compared to Adderall and is often covered by insurance, whereas Adderall is not.
